1. 个人简介:
徐合 博士,副教授。
教育经历:
2009.9-2014.6,博士,上海交通大学
2005.9-2009.6,学士,中国地质大学(武汉)
工作经历:
2018.9-至今,上海师范大学,副教授
2015.1-2017.6,上海师范大学,在职博士后
2014.7-2018.8,上海师范大学,讲师
2. 主要研究方向:
静电纺纳米纤维材料在生物医学中的应用,包括创面修复、骨/软骨缺损修复、药物及活性物质的控释等。
3. 代表性科研项目(主持):
(1)纳米生物玻璃修饰的图案化电纺纤维材料的制备及其创面修复的研究,国家自然科学青年基金,2016.01-2018.12;
(2)贻贝仿生高分子支架用于软骨组织的研究,上海市青年科技英才扬帆计划,2015.01-2017.12;
(3)具有气体治疗功能的金属有机骨架/电纺纤维复合材料用于促慢性创面修复的研究,上海市自然科学基金,2019.04-2022.3;
(4)微图案化有机/无机复合纳米纤维膜用于创面修复的研究,中国博士后科学基金面上基金一等资助,2015.09-2016.12;
(5)图案化复合纳米纤维膜用于创面修复的研究,纺织面料技术教育部重点实验室(东华大学)开放课题基金,2016.07-2017.12;
(6)仿生修饰高分子支架用于软骨组织工程的研究,上海高校青年教师培养资助计划,2015.01-2016.12;
(7)包载DNAseⅠ静电纺丝纳米纤维材料改善糖尿病难愈创面愈合,上海交通大学医学院转化医学协同创新中心合作研究项目,2018.01-2019.12;
(8)仿生修饰高分子组织工程支架的制备及其生物学性能的研究,上海师范大学一般科研项目,2015.01-2016.12。
4. 代表性论文及著作:
Jun Chen#, Dandan Sheng#, Ting Ying#, Haojun Zhao, Jian Zhang, Yunxia Li, He Xu* and Shiyi Chen*. Metal-organic frameworks-based nitric oxide therapy for tendon regeneration. Nano-Micro Letters.2021, 13, 23.
Yitong Wang†, Ting Ying†, Jinxiu Li†, Yafeng Xu, Qinfei Ke, Steve GF Shen*, He Xu* and Kaili Lin*. Hierarchical micro/nanofibrous scaffolds incorporated with curcumin and zinc ion eutectic metal organic frameworks for enhanced diabetic wound healing via anti-oxidant and anti-inflammatory activities.Chemical Engineering Journal. 2020, 402, 126273.
Xiaozhi Ren#, Jinxiu Li#, Jiayi Li#, Yuqi Jiang, Lan Li, Qingqiang Yao*, Qinfei Kea*, He Xu*. Aligned porous fibrous membrane with a biomimetic surface to acceleratecartilage regeneration. Chemical Engineering Journal, 2019, 370, 1027-1038.
He Xu†, Yu-Wei Ge†, Jia-Wei Lu, Qin-Fei Ke, Zhi-Qing Liu, Zhen-An Zhu*, Ya-Ping Guo*. Icariin loaded-hollow bioglass/chitosan therapeutic scaffolds promote osteogenic differentiation and bone regeneration. Chemical Engineering Journal, 2018, 354, 285-294.
Pengju Zhang, You Li, Yaohui Tang, Hui Shen, Jiankai Li, Zhengfang Yi*, Qinfei Ke*, and He Xu*. Copper-Based Metal-Organic Framework as A Controllable Nitric Oxide-Releasing Vehicle for Enhanced Diabetic Wound Healing. ACS Applied Materials & Interfaces, 2020, 12, 16, 18319-18331.
He Xu, Haiyan Li, Qinfei Ke, and Jiang Chang*. An Anisotropically and Heterogeneously Aligned Patterned Electrospun Scaffold with Tailored Mechanical Property and Improved Bioactivity for Vascular Tissue Engineering. ACS Applied Materials & Interfaces, 2015, 7, 8706-8718.
Jiankai Li, Fang Lv, Jinxiu Li, Jingduo Gao, Jian Luo, Feng Xue*, Qinfei Ke*, and He Xu*.Cobalt-based metal–organic framework as a dual cooperative controllable release system for accelerating diabetic wound healing. Nano Research, 2020, 13,2268-2279.
Jiafei Su, Cuilian Cheng, Yaping Guo, He Xu*, Qinfei Ke*. OMS-2-based catalysts with controllable hierarchical morphologies for highly efficient catalytic oxidation of formaldehyde. Journal of Hazardous Materials,2019, 380, 120890.
Ting Ying, Jiafei Su, Yijing Jiang, Qinfei Ke*, He Xu*. A pre-wetting induced superhydrophilic/superlipophilic micro-patterned electrospun membrane with self-cleaning property for on-demand emulsified oily wastewater separation. Journal of Hazardous Materials,2019, 121475.
Xiaozhi Ren†, Yiming Han†, Jie Wang, Yuqi Jiang, Zhengfang Yi*, He Xu*, Qinfei Ke*. An aligned porous electrospun fibrous membrane with controlled drug delivery – An efficient strategy to accelerate diabetic wound healing with improved angiogenesis. Acta Biomaterialia, 2018, 70, 140-153.
Fang Lv†, Jie Wang†, Peng Xu, Yiming Han, Hongshi Ma, He Xu*, Shijie Chen, Jiang Chang, Qinfei Ke, Mingyao Liu, Zhengfang Yi*, Chengtie Wu*. A conducive bioceramic/polymer composite biomaterial for diabetic wound healing, Acta Biomaterialia, 2017, 60, 128-143.
He Xu,† Fang Lv,† Yali Zhang,† Zhengfang Yi,* Qinfei Ke,* Chengtie Wu,* Mingyao Liu, Jiang Chang. Hierarchically micro-patterned nanofibrous scaffolds with nanosized bio-glass surface for accelerating wound healing. Nanoscale,2015, 7, 18446-18452.
5. 获奖情况:
2020.12获上海师范大学“优秀学术骨干”;
2017.12 获上海师范大学“优秀青年教师”;
2017.5获上海师范大学青年教师教学竞赛校级优秀奖,院级二等奖;
2016.1 获上海师范大学生命与环境科学学院“院长特别奖”;
邮箱地址:xuhe@shnu.edu.cn